Selective reduction of IFN-γ single positive mycobacteria-specific CD4+ T cells in HIV-1 infected individuals with latent tuberculosis infection

Selective reduction of IFN-γ single positive mycobacteria-specific CD4+ T cells in HIV-1 infected individuals with latent tuberculosis infection

HIV-1 is recognized to increase the risk for tuberculosis even before CD4+ T cell deficiency is profound. To better understand how HIV-1 alters immunity to latent tuberculosis, we compared the magnitude and functional profile of mycobacteria-specific CD4+ T cells between HIV-uninfected and HIV-infec...

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Bibliographic Details
Main Authors: Riou, Catherine, Bunjun, Rubina, Müller, Tracey L., Kiravu, Agano, Ginbot, Zekarias, Oni, Tolu, Goliath, Rene, Wilkinson, Robert J., Burgers, Wendy A.
Format: Online
Language:English
Published: Churchill Livingstone 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119638/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119638/

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