Aberrant DNA methylation of alternative promoter of DLC1 isoform 1 in meningiomas

Aberrant DNA methylation of alternative promoter of DLC1 isoform 1 in meningiomas

DLC1 encodes GTPase-activating protein with a well-documented tumor suppressor activity. This gene is downregulated in various tumors through aberrant promoter hypermethylation. Five different DLC1 isoforms can be transcribed from alternative promoters. Tumor-related DNA methylation of the DLC1 isof...

Full description

Bibliographic Details
Main Authors: Bujko, M., Kober, P., Rusetska, N., WakuĊ‚a, M., Goryca, K., Grecka, E., Matyja, E., Neska, J., Mandat, T., Bonicki, W., Siedlecki, J. A.
Format: Online
Language:English
Published: Springer US 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118400/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118400/

Similar Items