MEK inhibitors against MET-amplified non-small cell lung cancer

Several receptor tyrosine kinases (RTKs) including EGFR, ALK, and MET have been identified as therapeutic targets in non-small cell lung cancer (NSCLC). Among the downstream pathways of RTKs, the MAPK pathway is particularly important for cancer cell proliferation, differentiation, and survival. In...

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Bibliographic Details
Main Authors: Chiba, Masato, Togashi, Yosuke, Tomida, Shuta, Mizuuchi, Hiroshi, Nakamura, Yu, Banno, Eri, Hayashi, Hidetoshi, Terashima, Masato, De Velasco, Marco A., Sakai, Kazuko, Fujita, Yoshihiko, Mitsudomi, Tetsuya, Nishio, Kazuto
Format: Online
Language:English
Published: D.A. Spandidos 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118002/