New links between SOD1 and metabolic dysfunction from a yeast model of amyotrophic lateral sclerosis

New links between SOD1 and metabolic dysfunction from a yeast model of amyotrophic lateral sclerosis

A number of genes have been linked to familial forms of the fatal motor neuron disease amyotrophic lateral sclerosis (ALS). Over 150 mutations within the gene encoding superoxide dismutase 1 (SOD1) have been implicated in ALS, but why such mutations lead to ALS-associated cellular dysfunction is unc...

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Bibliographic Details
Main Authors: Bastow, Emma L., Peswani, Amber R., Tarrant, Daniel S. J., Pentland, Daniel R., Chen, Xi, Morgan, Alan, Staniforth, Gemma L., Tullet, Jennifer M., Rowe, Michelle L., Howard, Mark J., Tuite, Mick F., Gourlay, Campbell W.
Format: Online
Language:English
Published: The Company of Biologists Ltd 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117206/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117206/

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