Dendritic NMDA spikes are necessary for timing-dependent associative LTP in CA3 pyramidal cells

The computational repertoire of neurons is enhanced by regenerative electrical signals initiated in dendrites. These events, referred to as dendritic spikes, can act as cell-intrinsic amplifiers of synaptic input. Among these signals, dendritic NMDA spikes are of interest in light of their correlati...

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Bibliographic Details
Main Authors: Brandalise, Federico, Carta, Stefano, Helmchen, Fritjof, Lisman, John, Gerber, Urs
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116082/