p16INK4a Expression and Immunologic Aging in Chronic HIV Infection

Chronic HIV infection is characterized by increased immune activation and immunosenescence. p16 INK4a (p16) is a member of the cyclin-dependent kinase antagonist family that inhibits cellular proliferation, and its protein expression increases during normal chronological aging. However, some infecti...

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Bibliographic Details
Main Authors: Pereira Ribeiro, Susan, M. Milush, Jeffrey, Cunha-Neto, Edecio, G. Kallas, Esper, Kalil, Jorge, D. Passero, Luiz Felipe, W. Hunt, Peter, G. Deeks, Steven, F. Nixon, Douglas, SenGupta, Devi
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115792/