Metabolic flexibility of mitochondrial respiratory chain disorders predicted by computer modelling
Mitochondrial respiratory chain dysfunction causes a variety of life-threatening diseases affecting about 1 in 4300 adults. These diseases are genetically heterogeneous, but have the same outcome; reduced activity of mitochondrial respiratory chain complexes causing decreased ATP production and pote...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier Science
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115619/ |