Microglial phospholipase D4 deficiency influences myelination during brain development

Microglial phospholipase D4 deficiency influences myelination during brain development

Phospholipase D4 (PLD4) is expressed in activated microglia that transiently appear in white matter during postnatal brain development. Previous knockdown experiments using cultured microglia showed PLD4 involvement in phagocytosis and proliferation. To elucidate the role of PLD4 in vivo, PLD4-defic...

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Bibliographic Details
Main Authors:	CHIBA, Terumasa, OTANI, Yoshinori, YAMAGUCHI, Yoshihide, ISHIBASHI, Tomoko, HAYASHI, Akiko, TANAKA, Kenji F., YAMAZAKI, Maya, SAKIMURA, Kenji, BABA, Hiroko
Format:	Online
Language:	English
Published:	The Japan Academy 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114292/

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