Analysis of alternative lengthening of telomere markers in BRCA1 defective cells
Telomeres are specialized structures responsible for the chromosome end protection. Previous studies have revealed that defective BRCA1 may lead to elevated telomere fusions and accelerated telomere shortening. In addition, BRCA1 associates with promyelocytic leukemia (PML) bodies in alternative len...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
John Wiley and Sons Inc.
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113789/ |