Analysis of alternative lengthening of telomere markers in BRCA1 defective cells

Telomeres are specialized structures responsible for the chromosome end protection. Previous studies have revealed that defective BRCA1 may lead to elevated telomere fusions and accelerated telomere shortening. In addition, BRCA1 associates with promyelocytic leukemia (PML) bodies in alternative len...

Full description

Bibliographic Details
Main Authors: Kargaran, Parisa K., Yasaei, Hemad, Anjomaniā€Virmouni, Sara, Mangiapane, Giovanna, Slijepcevic, Predrag
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113789/