The host genetic background defines diverse immune-reactivity and susceptibility to chronic Pseudomonas aeruginosa respiratory infection

Patients with P. aeruginosa airways infection show markedly variable clinical phenotypes likely influenced by genetic backgrounds. Here, we investigated the cellular events involved in resistance and susceptibility to P. aeruginosa chronic infection using genetically distinct inbred mouse strains. A...

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Bibliographic Details
Main Authors: Spagnuolo, Lorenza, Simone, Maura De, Lorè, Nicola Ivan, Fino, Ida De, Basso, Veronica, Mondino, Anna, Cigana, Cristina, Bragonzi, Alessandra
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111113/