Hyperbaric oxygen increases tissue-plasminogen activator-induced thrombolysis in vitro, and reduces ischemic brain damage and edema in rats subjected to thromboembolic brain ischemia

Recent data have shown that normobaric oxygen (NBO) increases the catalytic and thrombolytic efficiency of recombinant tissue plasminogen activator (rtPA) in vitro, and is as efficient as rtPA at restoring cerebral blood flow in rats subjected to thromboembolic brain ischemia. Therefore, in the pres...

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Bibliographic Details
Main Authors: Chazalviel, Laurent, Haelewyn, Benoit, Degoulet, Mickael, Blatteau, Jean-Eric, Vallée, Nicolas, Risso, Jean-Jacques, Besnard, Stéphane, Abraini, Jacques H.
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110134/