Computational Drug Target Screening through Protein Interaction Profiles

The development of computational methods to discover novel drug-target interactions on a large scale is of great interest. We propose a new method for virtual screening based on protein interaction profile similarity to discover new targets for molecules, including existing drugs. We calculated Targ...

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Bibliographic Details
Main Authors: Vilar, Santiago, Quezada, Elías, Uriarte, Eugenio, Costanzi, Stefano, Borges, Fernanda, Viña, Dolores, Hripcsak, George
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109486/