Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase

The crystal structure of the liver isoform of human fructose-1,6-bisphosphatase in the active R-state conformation was determined by molecular replacement using data from a crystal with noncrystallographic rotational symmetry and pseudo-translation. Owing to an almost perfect placement of noncrystal...

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Main Authors:	Ruf, Armin, Tetaz, Tim, Schott, Brigitte, Joseph, Catherine, Rudolph, Markus G.
Format:	Online
Language:	English
Published:	International Union of Crystallography 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108348/

id	pubmed-5108348
recordtype	oai_dc
spelling	pubmed-51083482016-11-17 Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase Ruf, Armin Tetaz, Tim Schott, Brigitte Joseph, Catherine Rudolph, Markus G. Research Papers The crystal structure of the liver isoform of human fructose-1,6-bisphosphatase in the active R-state conformation was determined by molecular replacement using data from a crystal with noncrystallographic rotational symmetry and pseudo-translation. Owing to an almost perfect placement of noncrystallographic symmetry elements, quadruple space-group ambiguity within the same Laue symmetry arises, including two enantiogenic pairs. The origins of space-group ambiguity, the assignment of the correct space group, refinement and model properties are discussed. International Union of Crystallography 2016-10-28 /pmc/articles/PMC5108348/ /pubmed/27841754 http://dx.doi.org/10.1107/S2059798316016715 Text en © Ruf et al. 2016 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Ruf, Armin Tetaz, Tim Schott, Brigitte Joseph, Catherine Rudolph, Markus G.
spellingShingle	Ruf, Armin Tetaz, Tim Schott, Brigitte Joseph, Catherine Rudolph, Markus G. Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase
author_facet	Ruf, Armin Tetaz, Tim Schott, Brigitte Joseph, Catherine Rudolph, Markus G.
author_sort	Ruf, Armin
title	Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase
title_short	Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase
title_full	Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase
title_fullStr	Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase
title_full_unstemmed	Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase
title_sort	quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase
description	The crystal structure of the liver isoform of human fructose-1,6-bisphosphatase in the active R-state conformation was determined by molecular replacement using data from a crystal with noncrystallographic rotational symmetry and pseudo-translation. Owing to an almost perfect placement of noncrystallographic symmetry elements, quadruple space-group ambiguity within the same Laue symmetry arises, including two enantiogenic pairs. The origins of space-group ambiguity, the assignment of the correct space group, refinement and model properties are discussed.
publisher	International Union of Crystallography
publishDate	2016
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108348/
_version_	1613725977542656000

Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase

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