Activating Transcription Factor 4 (ATF4) modulates Rho GTPase levels and function via regulation of RhoGDIα

Activating Transcription Factor 4 (ATF4) modulates Rho GTPase levels and function via regulation of RhoGDIα

In earlier studies, we showed that ATF4 down-regulation affects post-synaptic development and dendritic spine morphology in neurons through increased turnover of the Rho GTPase Cell Division Cycle 42 (Cdc42) protein. Here, we find that ATF4 down-regulation in both hippocampal and cortical neuron cul...

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Bibliographic Details
Main Authors: Pasini, Silvia, Liu, Jin, Corona, Carlo, Peze-Heidsieck, Eugenie, Shelanski, Michael, Greene, Lloyd A.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107905/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107905/

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