CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State

CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State

Poly(A) tail length and mRNA deadenylation play important roles in gene regulation. However, how they regulate embryonic development and pluripotent cell fate is not fully understood. Here we present evidence that CNOT3-dependent mRNA deadenylation governs the pluripotent state. We show that CNOT3,...

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Bibliographic Details
Main Authors: Zheng, Xiaofeng, Yang, Pengyi, Lackford, Brad, Bennett, Brian D., Wang, Li, Li, Hui, Wang, Yu, Miao, Yiliang, Foley, Julie F., Fargo, David C., Jin, Ying, Williams, Carmen J., Jothi, Raja, Hu, Guang
Format: Online
Language:English
Published: Elsevier 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106518/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106518/

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