Chronic Progressive Neurodegeneration in a Transgenic Mouse Model of Prion Disease
Neurodegenerative diseases present pathologically with progressive structural destruction of neurons and accumulation of mis-folded proteins specific for each condition leading to brain atrophy and functional disability. Many animal models exert deposition of pathogenic proteins without an accompany...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104746/ |