Diurnal Variation of Circulating Interleukin-6 in Humans: A Meta-Analysis

The pleiotropic cytokine interleukin-6 (IL-6) has been proposed to contribute to circadian regulation of sleepiness by increasing in the blood at night. Earlier studies have reported diurnal variation of IL-6, but phase estimates are conflicting. We have therefore performed a meta-analysis on the di...

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Bibliographic Details
Main Authors: Nilsonne, Gustav, Lekander, Mats, Åkerstedt, Torbjörn, Axelsson, John, Ingre, Michael
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104468/