Cisplatin-induced regulation of signal transduction pathways and transcription factors in p53-mutated subclone variants of hepatoma cells: Potential application for therapeutic targeting

Cisplatin is commonly recognized as a DNA-damaging drug; however, its versatile antitumor effects have been demonstrated to extend beyond this narrow functional attribute. The present study determined how cisplatin regulates alternative pathways and transcription factors to exert its additional anti...

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Bibliographic Details
Main Authors: Kuo, Jinn-Rung, Shang, Hung-Sheng, Ho, Chun-Te, Lai, Kun-Goung, Liu, Tsan-Zon, Chen, Yin-Ju, Chiou, Jeng-Fong
Format: Online
Language:English
Published: D.A. Spandidos 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104157/