Is the glutamine story over?
Glutamine has been launched as a conditionally indispensible amino acid for the critically ill. Supplementation has been recommended in guidelines from international societies. Although data have been presented pointing out that glutamine supplementation may not be for everybody, recommendations for...
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pubmed-51035042016-11-14 Is the glutamine story over? Smedberg, Marie Wernerman, Jan Viewpoint Glutamine has been launched as a conditionally indispensible amino acid for the critically ill. Supplementation has been recommended in guidelines from international societies. Although data have been presented pointing out that glutamine supplementation may not be for everybody, recommendations for treatments and design of study protocols have included all critically ill patients. Results from more recent studies and meta-analyses indicate that indiscriminate use of glutamine supplementation in critically ill patients may actually cause harm rather than beneficial effects. This viewpoint sorts out arguments of controversy in the glutamine story. BioMed Central 2016-11-10 /pmc/articles/PMC5103504/ /pubmed/27829456 http://dx.doi.org/10.1186/s13054-016-1531-y Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Smedberg, Marie Wernerman, Jan |
spellingShingle |
Smedberg, Marie Wernerman, Jan Is the glutamine story over? |
author_facet |
Smedberg, Marie Wernerman, Jan |
author_sort |
Smedberg, Marie |
title |
Is the glutamine story over? |
title_short |
Is the glutamine story over? |
title_full |
Is the glutamine story over? |
title_fullStr |
Is the glutamine story over? |
title_full_unstemmed |
Is the glutamine story over? |
title_sort |
is the glutamine story over? |
description |
Glutamine has been launched as a conditionally indispensible amino acid for the critically ill. Supplementation has been recommended in guidelines from international societies. Although data have been presented pointing out that glutamine supplementation may not be for everybody, recommendations for treatments and design of study protocols have included all critically ill patients. Results from more recent studies and meta-analyses indicate that indiscriminate use of glutamine supplementation in critically ill patients may actually cause harm rather than beneficial effects. This viewpoint sorts out arguments of controversy in the glutamine story. |
publisher |
BioMed Central |
publishDate |
2016 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103504/ |
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1613721160941305856 |