Is the glutamine story over?

Glutamine has been launched as a conditionally indispensible amino acid for the critically ill. Supplementation has been recommended in guidelines from international societies. Although data have been presented pointing out that glutamine supplementation may not be for everybody, recommendations for...

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Main Authors: Smedberg, Marie, Wernerman, Jan
Format: Online
Language:English
Published: BioMed Central 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103504/
id pubmed-5103504
recordtype oai_dc
spelling pubmed-51035042016-11-14 Is the glutamine story over? Smedberg, Marie Wernerman, Jan Viewpoint Glutamine has been launched as a conditionally indispensible amino acid for the critically ill. Supplementation has been recommended in guidelines from international societies. Although data have been presented pointing out that glutamine supplementation may not be for everybody, recommendations for treatments and design of study protocols have included all critically ill patients. Results from more recent studies and meta-analyses indicate that indiscriminate use of glutamine supplementation in critically ill patients may actually cause harm rather than beneficial effects. This viewpoint sorts out arguments of controversy in the glutamine story. BioMed Central 2016-11-10 /pmc/articles/PMC5103504/ /pubmed/27829456 http://dx.doi.org/10.1186/s13054-016-1531-y Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Smedberg, Marie
Wernerman, Jan
spellingShingle Smedberg, Marie
Wernerman, Jan
Is the glutamine story over?
author_facet Smedberg, Marie
Wernerman, Jan
author_sort Smedberg, Marie
title Is the glutamine story over?
title_short Is the glutamine story over?
title_full Is the glutamine story over?
title_fullStr Is the glutamine story over?
title_full_unstemmed Is the glutamine story over?
title_sort is the glutamine story over?
description Glutamine has been launched as a conditionally indispensible amino acid for the critically ill. Supplementation has been recommended in guidelines from international societies. Although data have been presented pointing out that glutamine supplementation may not be for everybody, recommendations for treatments and design of study protocols have included all critically ill patients. Results from more recent studies and meta-analyses indicate that indiscriminate use of glutamine supplementation in critically ill patients may actually cause harm rather than beneficial effects. This viewpoint sorts out arguments of controversy in the glutamine story.
publisher BioMed Central
publishDate 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103504/
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