Functional characterization of EI24-induced autophagy in the degradation of RING-domain E3 ligases

Historically, the ubiquitin-proteasome system (UPS) and autophagy pathways were believed to be independent; however, recent data indicate that these pathways engage in crosstalk. To date, the players mediating this crosstalk have been elusive. Here, we show experimentally that EI24 (EI24, autophagy...

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Bibliographic Details
Main Authors: Devkota, Sushil, Jeong, Hyobin, Kim, Yunmi, Ali, Muhammad, Roh, Jae-il, Hwang, Daehee, Lee, Han-Woong
Format: Online
Language:English
Published: Taylor & Francis 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103340/