Inhibition of Epac1 suppresses mitochondrial fission and reduces neointima formation induced by vascular injury

Vascular smooth muscle cell (VSMC) activation in response to injury plays an important role in the development of vascular proliferative diseases, including restenosis and atherosclerosis. The aims of this study were to ascertain the physiological functions of exchange proteins directly activated by...

Full description

Bibliographic Details
Main Authors: Wang, Hui, Robichaux, William G., Wang, Ziqing, Mei, Fang C., Cai, Ming, Du, Guangwei, Chen, Ju, Cheng, Xiaodong
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103196/