A painful neuropathy-associated Nav1.7 mutant leads to time-dependent degeneration of small-diameter axons associated with intracellular Ca2+ dysregulation and decrease in ATP levels
Small fiber neuropathy is a painful sensory nervous system disorder characterized by damage to unmyelinated C- and thinly myelinated Aδ- nerve fibers, clinically manifested by burning pain in the distal extremities and dysautonomia. The clinical onset in adulthood suggests a time-dependent process....
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
SAGE Publications
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102167/ |