Mitochondrial Ca2+ uptake controls actin cytoskeleton dynamics during cell migration

Intracellular Ca2+ signaling regulates cell migration by acting on cytoskeleton architecture, cell directionality and focal adhesions dynamics. In migrating cells, cytosolic Ca2+ pool and Ca2+ pulses are described as key components of these effects. Whereas the role of the mitochondrial calcium home...

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Bibliographic Details
Main Authors: Prudent, Julien, Popgeorgiev, Nikolay, Gadet, Rudy, Deygas, Mathieu, Rimokh, Ruth, Gillet, Germain
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101530/