Efficient derivation of microglia-like cells from human pluripotent stem cells

Microglia, the only lifelong resident immune cells of the central nervous system (CNS), are highly specialized macrophages which have been recognized to play a crucial role in neurodegenerative diseases such as Alzheimer’s, Parkinson’s and Adrenoleukodystrophy (ALD). However, in contrast to other ce...

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Bibliographic Details
Main Authors: Muffat, Julien, Li, Yun, Yuan, Bingbing, Mitalipova, Maisam, Omer, Attya, Corcoran, Sean, Bakiasi, Grisilda, Tsai, Li-Huei, Aubourg, Patrick, Ransohoff, Richard M., Jaenisch, Rudolf
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101156/