Skin Vaccination against Rotavirus Using Microneedles: Proof of Concept in Gnotobiotic Piglets
Live-attenuated oral rotavirus (RV) vaccines have lower efficacy in low income countries, and additionally are associated with a rare but severe adverse event, intussusception. We have been pursuing the development of an inactivated rotavirus vaccine (IRV) using the human rotavirus strain CDC-9 (G1P...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100943/ |