Association of lactase persistence genotype with milk consumption, obesity and blood pressure: a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysis

Background: Milk intake has been associated with lower blood pressure (BP) in observational studies, and randomized controlled trials suggested that milk-derived tripeptides have BP-lowering effects. Milk intake has also been associated with body mass index (BMI). Nevertheless, it is unclear whethe...

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Main Authors: Hartwig, Fernando Pires, Horta, Bernardo Lessa, Smith, George Davey, de Mola, Christian Loret, Victora, Cesar Gomes
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100608/
id pubmed-5100608
recordtype oai_dc
spelling pubmed-51006082016-11-10 Association of lactase persistence genotype with milk consumption, obesity and blood pressure: a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysis Hartwig, Fernando Pires Horta, Bernardo Lessa Smith, George Davey de Mola, Christian Loret Victora, Cesar Gomes Mendelian Randomization Background: Milk intake has been associated with lower blood pressure (BP) in observational studies, and randomized controlled trials suggested that milk-derived tripeptides have BP-lowering effects. Milk intake has also been associated with body mass index (BMI). Nevertheless, it is unclear whether increasing milk consumption would reduce BP in the general population. Oxford University Press 2016-10 2016-05-11 /pmc/articles/PMC5100608/ /pubmed/27170764 http://dx.doi.org/10.1093/ije/dyw074 Text en © The Author 2016. Published by Oxford University Press on behalf of the International Epidemiological Association http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Hartwig, Fernando Pires
Horta, Bernardo Lessa
Smith, George Davey
de Mola, Christian Loret
Victora, Cesar Gomes
spellingShingle Hartwig, Fernando Pires
Horta, Bernardo Lessa
Smith, George Davey
de Mola, Christian Loret
Victora, Cesar Gomes
Association of lactase persistence genotype with milk consumption, obesity and blood pressure: a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysis
author_facet Hartwig, Fernando Pires
Horta, Bernardo Lessa
Smith, George Davey
de Mola, Christian Loret
Victora, Cesar Gomes
author_sort Hartwig, Fernando Pires
title Association of lactase persistence genotype with milk consumption, obesity and blood pressure: a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysis
title_short Association of lactase persistence genotype with milk consumption, obesity and blood pressure: a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysis
title_full Association of lactase persistence genotype with milk consumption, obesity and blood pressure: a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysis
title_fullStr Association of lactase persistence genotype with milk consumption, obesity and blood pressure: a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysis
title_full_unstemmed Association of lactase persistence genotype with milk consumption, obesity and blood pressure: a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysis
title_sort association of lactase persistence genotype with milk consumption, obesity and blood pressure: a mendelian randomization study in the 1982 pelotas (brazil) birth cohort, with a systematic review and meta-analysis
description Background: Milk intake has been associated with lower blood pressure (BP) in observational studies, and randomized controlled trials suggested that milk-derived tripeptides have BP-lowering effects. Milk intake has also been associated with body mass index (BMI). Nevertheless, it is unclear whether increasing milk consumption would reduce BP in the general population.
publisher Oxford University Press
publishDate 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100608/
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