Loss and Gain of Human Acidic Mammalian Chitinase Activity by Nonsynonymous SNPs

Loss and Gain of Human Acidic Mammalian Chitinase Activity by Nonsynonymous SNPs

Acidic mammalian chitinase (AMCase) is implicated in asthma, allergic inflammation, and food processing. Little is known about genetic and evolutional regulation of chitinolytic activity of AMCase. Here, we relate human AMCase polymorphisms to the mouse AMCase, and show that the highly active varian...

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Bibliographic Details
Main Authors: Okawa, Kazuaki, Ohno, Misa, Kashimura, Akinori, Kimura, Masahiro, Kobayashi, Yuki, Sakaguchi, Masayoshi, Sugahara, Yasusato, Kamaya, Minori, Kino, Yoshihiro, Bauer, Peter O., Oyama, Fumitaka
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100053/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100053/

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