Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish

Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish

CALR mutations are identified in about 30% of JAK2/MPL-unmutated myeloproliferative neoplasms (MPNs) including essential thrombocythemia (ET) and primary myelofibrosis. Although the molecular pathogenesis of CALR mutations leading to MPNs has been studied using in vitro cell lines models, how mutant...

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Bibliographic Details
Main Authors: Lim, K-H, Chang, Y-C, Chiang, Y-H, Lin, H-C, Chang, C-Y, Lin, C-S, Huang, L, Wang, W-T, Gon-Shen Chen, C, Chou, W-C, Kuo, Y-Y
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098260/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098260/

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