ISL1-based LIM complexes control Slit2 transcription in developing cranial motor neurons

ISL1-based LIM complexes control Slit2 transcription in developing cranial motor neurons

LIM-homeodomain (HD) transcription factors form a multimeric complex and assign neuronal subtype identities, as demonstrated by the hexameric ISL1-LHX3 complex which gives rise to somatic motor (SM) neurons. However, the roles of combinatorial LIM code in motor neuron diversification and their subse...

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Bibliographic Details
Main Authors: Kim, Kyung-Tai, Kim, Namhee, Kim, Hwan-Ki, Lee, Hojae, Gruner, Hannah N., Gergics, Peter, Park, Chungoo, Mastick, Grant S., Park, Hae-Chul, Song, Mi-Ryoung
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098159/

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