Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer's pathology

There is considerable debate whether Alzheimer's disease (AD) originates in basal forebrain or entorhinal cortex. Here we examined whether longitudinal decreases in basal forebrain and entorhinal cortex grey matter volume were interdependent and sequential. In a large cohort of age-matched olde...

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Bibliographic Details
Main Authors: Schmitz, Taylor W., Nathan Spreng, R.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097157/