Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging

The study of amyotrophic lateral sclerosis (ALS) and potential interventions would be facilitated if motor axon degeneration could be more readily visualized. Here we demonstrate that stimulated Raman scattering (SRS) microscopy could be used to sensitively monitor peripheral nerve degeneration in A...

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Bibliographic Details
Main Authors: Tian, Feng, Yang, Wenlong, Mordes, Daniel A., Wang, Jin-Yuan, Salameh, Johnny S., Mok, Joanie, Chew, Jeannie, Sharma, Aarti, Leno-Duran, Ester, Suzuki-Uematsu, Satomi, Suzuki, Naoki, Han, Steve S., Lu, Fa-Ke, Ji, Minbiao, Zhang, Rosanna, Liu, Yue, Strominger, Jack, Shneider, Neil A., Petrucelli, Leonard, Xie, X. Sunney, Eggan, Kevin
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095598/