Association of EGFR Exon 19 Deletion and EGFR-TKI Treatment Duration with Frequency of T790M Mutation in EGFR-Mutant Lung Cancer Patients

Association of EGFR Exon 19 Deletion and EGFR-TKI Treatment Duration with Frequency of T790M Mutation in EGFR-Mutant Lung Cancer Patients

The most common event responsible for resistance to first- and second-generation (1st and 2nd) epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI) is acquisition of T790M mutation. We examined whether T790M is related to clinicopathologic or prognostic factors in patients with re...

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Bibliographic Details
Main Authors: Matsuo, Norikazu, Azuma, Koichi, Sakai, Kazuko, Hattori, Satoshi, Kawahara, Akihiko, Ishii, Hidenobu, Tokito, Takaaki, Kinoshita, Takashi, Yamada, Kazuhiko, Nishio, Kazuto, Hoshino, Tomoaki
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095551/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095551/

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