IL-1β, But Not Programed Death-1 and Programed Death Ligand Pathway, Is Critical for the Human Th17 Response to Mycobacterium tuberculosis

IL-1β, But Not Programed Death-1 and Programed Death Ligand Pathway, Is Critical for the Human Th17 Response to Mycobacterium tuberculosis

The programed death-1 (PD-1)–programed death ligand-1 (PD-L1) and PD-L2 co-inhibitory pathway has been implicated in the evasion strategies of Mycobacterium tuberculosis. Specifically, M. tuberculosis-induced PD-L1 orchestrates expansion of regulatory T cells and suppression of Th1 response. However...

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Bibliographic Details
Main Authors: Stephen-Victor, Emmanuel, Sharma, Varun Kumar, Das, Mrinmoy, Karnam, Anupama, Saha, Chaitrali, Lecerf, Maxime, Galeotti, Caroline, Kaveri, Srinivas V., Bayry, Jagadeesh
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095489/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095489/

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