Cathelicidin Insufficiency in Patients with Fatal Leptospirosis

Leptospirosis causes significant morbidity and mortality worldwide; however, the role of the host immune response in disease progression and high case fatality (>10–50%) is poorly understood. We conducted a multi-parameter investigation of patients with acute leptospirosis to identify mechanisms...

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Bibliographic Details
Main Authors: Lindow, Janet C., Wunder, Elsio A., Popper, Stephen J., Min, Jin-na, Mannam, Praveen, Srivastava, Anup, Yao, Yi, Hacker, Kathryn P., Raddassi, Khadir, Lee, Patty J., Montgomery, Ruth R., Shaw, Albert C., Hagan, Jose E., Araújo, Guilherme C., Nery, Nivison, Relman, David A., Kim, Charles C., Reis, Mitermayer G., Ko, Albert I.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094754/