Significant impact of biochemical recurrence on overall mortality in patients with high‐risk prostate cancer after carbon‐ion radiotherapy combined with androgen deprivation therapy

Significant impact of biochemical recurrence on overall mortality in patients with high‐risk prostate cancer after carbon‐ion radiotherapy combined with androgen deprivation therapy

Two prospective phase 2 studies involving 324 high‐risk prostate cancer patients treated with carbon‐ion radiotherapy have revealed that the presence of biochemical recurrence is an independent predictive factor for overall mortality (hazard ratio, 2.82; 95% confidence interval, 1.57‐5.08; P = .001)...

Full description

Bibliographic Details
Main Authors: Kasuya, Goro, Ishikawa, Hitoshi, Tsuji, Hiroshi, Nomiya, Takuma, Makishima, Hirokazu, Kamada, Tadashi, Akakura, Koichiro, Suzuki, Hiroyoshi, Shimazaki, Jun, Haruyama, Yasuo, Kobashi, Gen, Tsujii, Hirohiko
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094521/
id pubmed-5094521
recordtype oai_dc
spelling pubmed-50945212016-11-09 Significant impact of biochemical recurrence on overall mortality in patients with high‐risk prostate cancer after carbon‐ion radiotherapy combined with androgen deprivation therapy Kasuya, Goro Ishikawa, Hitoshi Tsuji, Hiroshi Nomiya, Takuma Makishima, Hirokazu Kamada, Tadashi Akakura, Koichiro Suzuki, Hiroyoshi Shimazaki, Jun Haruyama, Yasuo Kobashi, Gen Tsujii, Hirohiko Original Articles Two prospective phase 2 studies involving 324 high‐risk prostate cancer patients treated with carbon‐ion radiotherapy have revealed that the presence of biochemical recurrence is an independent predictive factor for overall mortality (hazard ratio, 2.82; 95% confidence interval, 1.57‐5.08; P = .001) in patients with high‐risk prostate cancer after carbon‐ion radiotherapy according to a multivariate analysis. John Wiley and Sons Inc. 2016-06-28 2016-10-15 /pmc/articles/PMC5094521/ /pubmed/27351298 http://dx.doi.org/10.1002/cncr.30050 Text en © 2016 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Kasuya, Goro
Ishikawa, Hitoshi
Tsuji, Hiroshi
Nomiya, Takuma
Makishima, Hirokazu
Kamada, Tadashi
Akakura, Koichiro
Suzuki, Hiroyoshi
Shimazaki, Jun
Haruyama, Yasuo
Kobashi, Gen
Tsujii, Hirohiko
spellingShingle Kasuya, Goro
Ishikawa, Hitoshi
Tsuji, Hiroshi
Nomiya, Takuma
Makishima, Hirokazu
Kamada, Tadashi
Akakura, Koichiro
Suzuki, Hiroyoshi
Shimazaki, Jun
Haruyama, Yasuo
Kobashi, Gen
Tsujii, Hirohiko
Significant impact of biochemical recurrence on overall mortality in patients with high‐risk prostate cancer after carbon‐ion radiotherapy combined with androgen deprivation therapy
author_facet Kasuya, Goro
Ishikawa, Hitoshi
Tsuji, Hiroshi
Nomiya, Takuma
Makishima, Hirokazu
Kamada, Tadashi
Akakura, Koichiro
Suzuki, Hiroyoshi
Shimazaki, Jun
Haruyama, Yasuo
Kobashi, Gen
Tsujii, Hirohiko
author_sort Kasuya, Goro
title Significant impact of biochemical recurrence on overall mortality in patients with high‐risk prostate cancer after carbon‐ion radiotherapy combined with androgen deprivation therapy
title_short Significant impact of biochemical recurrence on overall mortality in patients with high‐risk prostate cancer after carbon‐ion radiotherapy combined with androgen deprivation therapy
title_full Significant impact of biochemical recurrence on overall mortality in patients with high‐risk prostate cancer after carbon‐ion radiotherapy combined with androgen deprivation therapy
title_fullStr Significant impact of biochemical recurrence on overall mortality in patients with high‐risk prostate cancer after carbon‐ion radiotherapy combined with androgen deprivation therapy
title_full_unstemmed Significant impact of biochemical recurrence on overall mortality in patients with high‐risk prostate cancer after carbon‐ion radiotherapy combined with androgen deprivation therapy
title_sort significant impact of biochemical recurrence on overall mortality in patients with high‐risk prostate cancer after carbon‐ion radiotherapy combined with androgen deprivation therapy
description Two prospective phase 2 studies involving 324 high‐risk prostate cancer patients treated with carbon‐ion radiotherapy have revealed that the presence of biochemical recurrence is an independent predictive factor for overall mortality (hazard ratio, 2.82; 95% confidence interval, 1.57‐5.08; P = .001) in patients with high‐risk prostate cancer after carbon‐ion radiotherapy according to a multivariate analysis.
publisher John Wiley and Sons Inc.
publishDate 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094521/
_version_ 1613712006127288320

Similar Items