Epigallocatechin-3-gallate enhances key enzymatic activities of hepatic thioredoxin and glutathione systems in selenium-optimal mice but activates hepatic Nrf2 responses in selenium-deficient mice
Selenium participates in the antioxidant defense mainly through a class of selenoproteins, including thioredoxin reductase. Epigallocatechin-3-gallate (EGCG) is the most abundant and biologically active catechin in green tea. Depending upon the dose and biological systems, EGCG may function either a...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Elsevier
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094413/ |