mTORC1 inhibitor rapamycin and ER stressor tunicamycin induce differential patterns of ER-mitochondria coupling

mTORC1 inhibitor rapamycin and ER stressor tunicamycin induce differential patterns of ER-mitochondria coupling

Efficient mitochondrial Ca2+ uptake takes place at contact points between the ER and mitochondria, and represents a key regulator of many cell functions. In a previous study with HeLa cells, we showed that ER-to-mitochondria Ca2+ transfer increases during the early phase of ER stress induced by tuni...

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Bibliographic Details
Main Authors: Bravo-Sagua, Roberto, López-Crisosto, Camila, Parra, Valentina, Rodriguez-Peña, Marcelo, Rothermel, Beverly A., Quest, Andrew F.G., Lavandero, Sergio
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093439/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093439/

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