Self-assembling peptide nanofibers containing phenylalanine for the controlled release of 5-fluorouracil

Self-assembling peptide nanofibers containing phenylalanine for the controlled release of 5-fluorouracil

The study shows that RADA-F6 peptide with pH-responsive self-assembling nature can be effectively used as a drug delivery system for the sustained release of a potent anticancer drug 5-fluorouracil (5-FU) at basic pH. As 5-FU contains the aromatic pyrimidine ring, RADA-F6 system is suitable for entr...

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Bibliographic Details
Main Authors: Ashwanikumar, Narayanan, Kumar, Nisha Asok, Saneesh Babu, Padma S, Sivakumar, Krishnankutty C, Vadakkan, Mithun Varghese, Nair, Parvathi, Hema Saranya, Ilamathi, Asha Nair, Sivakumari, Vinod Kumar, Gopalakrishnapillai S
Format: Online
Language:English
Published: Dove Medical Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087806/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087806/

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