MECP2 promotes the growth of gastric cancer cells by suppressing miR-338-mediated antiproliferative effect

MECP2 promotes the growth of gastric cancer cells by suppressing miR-338-mediated antiproliferative effect

The methyl-CpG-binding protein 2 (MECP2), a transcriptional suppressor, is involved in gene regulation by binding to methylated promoters. We found that MECP2 is overexpressed in gastric cancer (GC), and that Mecp2 knockdown affects the growth of GC cells both in vitro and in vivo. MECP2 can directl...

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Bibliographic Details
Main Authors: Tong, Dongdong, Zhao, Lingyu, He, Kang, Sun, Hongfei, Cai, Donghui, Ni, Lei, Sun, Ruifang, Chang, Su'e, Song, Tusheng, Huang, Chen
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085194/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085194/

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