FXR agonists enhance the sensitivity of biliary tract cancer cells to cisplatin via SHP dependent inhibition of Bcl-xL expression

FXR agonists enhance the sensitivity of biliary tract cancer cells to cisplatin via SHP dependent inhibition of Bcl-xL expression

Chemoresistance is common in patients with biliary tract cancer (BTC) including gallbladder cancer (GBC) and cholangiocarcinoma (CC). Therefore, it is necessary to identify effective chemotherapeutic agents for BTC. In the present study, we for the first time tested the effect of farnesoid X recepto...

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Bibliographic Details
Main Authors: Wang, Wei, Zhan, Ming, Li, Qi, Chen, Wei, Chu, Huiling, Huang, Qihong, Hou, Zhaoyuan, Man, Mohan, Wang, Jian
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085180/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085180/

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