Autophagy suppresses cell migration by degrading GEF-H1, a RhoA GEF

Cell migration is a process crucial for a variety of biological events, such as morphogenesis and wound healing. Several reports have described the possible regulation of cell migration by autophagy; however, this remains controversial. We here demonstrate that mouse embryonic fibroblasts (MEFs) lac...

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Bibliographic Details
Main Authors: Yoshida, Tatsushi, Tsujioka, Masatsune, Honda, Shinya, Tanaka, Masato, Shimizu, Shigeomi
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085165/