Temperature-Dependent Model of Multi-step Transcription Initiation in Escherichia coli Based on Live Single-Cell Measurements

Transcription kinetics is limited by its initiation steps, which differ between promoters and with intra- and extracellular conditions. Regulation of these steps allows tuning both the rate and stochasticity of RNA production. We used time-lapse, single-RNA microscopy measurements in live Escherichi...

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Bibliographic Details
Main Authors: Oliveira, Samuel M. D., Häkkinen, Antti, Lloyd-Price, Jason, Tran, Huy, Kandavalli, Vinodh, Ribeiro, Andre S.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085040/