DNA sensor cGAS-mediated immune recognition

The host takes use of pattern recognition receptors (PRRs) to defend against pathogen invasion or cellular damage. Among microorganism-associated molecular patterns detected by host PRRs, nucleic acids derived from bacteria or viruses are tightly supervised, providing a fundamental mechanism of host...

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Bibliographic Details
Main Authors: Xia, Pengyan, Wang, Shuo, Gao, Pu, Gao, Guangxia, Fan, Zusen
Format: Online
Language:English
Published: Higher Education Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084157/