Comet Lesions in Patients with Pseudoxanthoma Elasticum

Comet Lesions in Patients with Pseudoxanthoma Elasticum

Pseudoxanthoma elasticum (PXE) is a genetic multisystemic disorder affecting the skin, eyes and cardiovascular system. Basic fundoscopic findings in PXE result from Bruch’s membrane involvement. The most important fundoscopic findings are angioid streaks. Other significant ocular findings are peau d...

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Main Authors: Tatlıpınar, Sinan, Şahan, Berna, Altunsoy, Muhsin
Format: Online
Language:English
Published: Galenos Publishing 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082266/
id pubmed-5082266
recordtype oai_dc
spelling pubmed-50822662016-10-31 Comet Lesions in Patients with Pseudoxanthoma Elasticum Tatlıpınar, Sinan Şahan, Berna Altunsoy, Muhsin Case Report Pseudoxanthoma elasticum (PXE) is a genetic multisystemic disorder affecting the skin, eyes and cardiovascular system. Basic fundoscopic findings in PXE result from Bruch’s membrane involvement. The most important fundoscopic findings are angioid streaks. Other significant ocular findings are peau d’orange appearance, optic disc drusen, pattern dystrophy-like macular appearance, comet lesions, and choroidal neovascularization. Comet lesions are a pathognomonic ocular finding for PXE. The presence of both angioid streaks in the fundus and typical skin lesions should alert clinicians to PXE. Herein, we present two PXE cases with comet lesions. Galenos Publishing 2015-12 2015-12-05 /pmc/articles/PMC5082266/ /pubmed/27800246 http://dx.doi.org/10.4274/tjo.84756 Text en ©Turkish Journal of Ophthalmology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Tatlıpınar, Sinan
Şahan, Berna
Altunsoy, Muhsin
spellingShingle Tatlıpınar, Sinan
Şahan, Berna
Altunsoy, Muhsin
Comet Lesions in Patients with Pseudoxanthoma Elasticum
author_facet Tatlıpınar, Sinan
Şahan, Berna
Altunsoy, Muhsin
author_sort Tatlıpınar, Sinan
title Comet Lesions in Patients with Pseudoxanthoma Elasticum
title_short Comet Lesions in Patients with Pseudoxanthoma Elasticum
title_full Comet Lesions in Patients with Pseudoxanthoma Elasticum
title_fullStr Comet Lesions in Patients with Pseudoxanthoma Elasticum
title_full_unstemmed Comet Lesions in Patients with Pseudoxanthoma Elasticum
title_sort comet lesions in patients with pseudoxanthoma elasticum
description Pseudoxanthoma elasticum (PXE) is a genetic multisystemic disorder affecting the skin, eyes and cardiovascular system. Basic fundoscopic findings in PXE result from Bruch’s membrane involvement. The most important fundoscopic findings are angioid streaks. Other significant ocular findings are peau d’orange appearance, optic disc drusen, pattern dystrophy-like macular appearance, comet lesions, and choroidal neovascularization. Comet lesions are a pathognomonic ocular finding for PXE. The presence of both angioid streaks in the fundus and typical skin lesions should alert clinicians to PXE. Herein, we present two PXE cases with comet lesions.
publisher Galenos Publishing
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082266/
_version_ 1613700130919153664

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