Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle

•Defective skeletal muscle G6PDH activity in multiple insulin resistant animal models.•Demonstration of defective skeletal muscle G6PDH activity in pre-diabetic individuals.•Identification of nNOSμ as a regulator of G6PDH activity in skeletal muscle.•G6PDH activity modulates insulin-independent gluc...

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Bibliographic Details
Main Authors: Lee-Young, Robert S., Hoffman, Nolan J., Murphy, Kate T., Henstridge, Darren C., Samocha-Bonet, Dorit, Siebel, Andrew L., Iliades, Peter, Zivanovic, Borivoj, Hong, Yet H., Colgan, Timothy D., Kraakman, Michael J., Bruce, Clinton R., Gregorevic, Paul, McConell, Glenn K., Lynch, Gordon S., Drummond, Grant R., Kingwell, Bronwyn A., Greenfield, Jerry R., Febbraio, Mark A.
Format: Online
Language:English
Published: Elsevier 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081409/