HLA class II sequence variants influence tuberculosis risk in populations of European ancestry

HLA class II sequence variants influence tuberculosis risk in populations of European ancestry

Mycobacterium tuberculosis (M. tuberculosis) infections cause 9.0 million new tuberculosis (TB) cases and 1.5 million deaths annually1. To search for sequence variants that confer risk of TB we tested 28.3 million variants identified through whole-genome sequencing of 2,636 Icelanders for associatio...

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Main Authors: Sveinbjornsson, Gardar, Gudbjartsson, Daniel F., Halldorsson, Bjarni V., Kristinsson, Karl G., Gottfredsson, Magnus, Barrett, Jeffrey C., Gudmundsson, Larus J., Blondal, Kai, Gylfason, Arnaldur, Gudjonsson, Sigurjon Axel, Helgadottir, Hafdis T., Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Karason, Ari, Kardum, Ljiljana Bulat, Knežević, Jelena, Kristjansson, Helgi, Kristjansson, Mar, Love, Arthur, Luo, Yang, Magnusson, Olafur T., Sulem, Patrick, Kong, Augustine, Masson, Gisli, Thorsteinsdottir, Unnur, Dembic, Zlatko, Nejentsev, Sergey, Blondal, Thorsteinn, Jonsdottir, Ingileif, Stefansson, Kari
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081101/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081101/

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