Combined Toxic Effects of Polar and Nonpolar Chemicals on Human Hepatocytes (HepG2) Cells by Quantitative Property-Activity Relationship Modeling

Combined Toxic Effects of Polar and Nonpolar Chemicals on Human Hepatocytes (HepG2) Cells by Quantitative Property-Activity Relationship Modeling

We determined the toxicity of mixtures of ethyl acetate (EA), isopropyl alcohol (IPA), methyl ethyl ketone (MEK), toluene (TOL) and xylene (XYL) with half-maximal effective concentration (EC50) values obtained using human hepatocytes cells. According to these data, quantitative property-activity rel...

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Bibliographic Details
Main Authors: Kim, Ki-Woong, Won, Yong Lim, Park, Dong Jin, Kim, Young Sun, Jin, Eun Sil, Lee, Sung Kwang
Format: Online
Language:English
Published: Korean Society of Toxicology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080860/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080860/

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