Autoantibodies against Modified Histone Peptides in SLE Patients Are Associated with Disease Activity and Lupus Nephritis

Autoantibodies against Modified Histone Peptides in SLE Patients Are Associated with Disease Activity and Lupus Nephritis

Persistent exposure of the immune system to death cell debris leads to autoantibodies against chromatin in patients with systemic lupus erythematosus (SLE). Deposition of anti-chromatin/chromatin complexes can instigate inflammation in multiple organs including the kidney. Previously we identified s...

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Bibliographic Details
Main Authors: Dieker, Jürgen, Berden, Jo H., Bakker, Marinka, Briand, Jean-Paul, Muller, Sylviane, Voll, Reinhard, Sjöwall, Christopher, Herrmann, Martin, Hilbrands, Luuk B., van der Vlag, Johan
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079581/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079581/

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