Palmitoylation regulates the intracellular trafficking and stability of c-Met
c-Met is a receptor tyrosine kinase whose activity can promote both mitogenic and motogenic phenotypes involved in tissue development and cancer progression. Herein, we report the first evidence that c-Met is palmitoylated and that palmitoylation facilitates its trafficking and stability. Inhibition...
Main Authors: | Coleman, David T., Gray, Alana L., Kridel, Steven J., Cardelli, James A. |
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Format: | Online |
Language: | English |
Published: |
Impact Journals LLC
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078042/ |
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