Stretching human mesenchymal stromal cells on stiffness-customized collagen type I generates a smooth muscle marker profile without growth factor addition

Stretching human mesenchymal stromal cells on stiffness-customized collagen type I generates a smooth muscle marker profile without growth factor addition

Using matrix elasticity and cyclic stretch have been investigated for inducing mesenchymal stromal cell (MSC) differentiation towards the smooth muscle cell (SMC) lineage but not in combination. We hypothesized that combining lineage-specific stiffness with cyclic stretch would result in a significa...

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Bibliographic Details
Main Authors: Rothdiener, Miriam, Hegemann, Miriam, Uynuk-Ool, Tatiana, Walters, Brandan, Papugy, Piruntha, Nguyen, Phong, Claus, Valentin, Seeger, Tanja, Stoeckle, Ulrich, Boehme, Karen A., Aicher, Wilhelm K., Stegemann, Jan P., Hart, Melanie L., Kurz, Bodo, Klein, Gerd, Rolauffs, Bernd
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075785/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075785/

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